Mass spectrometry facility

The Central Analytical Laboratory facility, located in room C1B90 in the JSC Biotechnology Building, currently houses several Waters UPLCs and six mass spectrometers to provide structural information on various samples (from small organic molecules to large proteins). The facility is available to analyze samples from both University of Colorado and non-CU sources.

The following instruments are housed in the facility:

ManufacturerModelMass AnalyzerIonization Methods
ABI Voyager-DE™ STR Time-of-Flight (ToF) MALDI
ABI 4000 Q TRAP® LC/MS/MS System Triple quadrupole / Linear Ion Trap ESI, nanospray
Thermo Finnigan LTQ Orbitrap Velos LTQ Dual-Ion Trap / Orbitrap ESI
Thermo Finnigan LTQ Orbitrap LTQ Ion Trap / Orbitrap ESI
Thermo Finnigan PolarisQ Ion Trap GC/MSn Ion Trap EI
Waters Synapt G2 HDMS Quadrupole / ToF ESI

Our instruments are used to confirm the identity of various organic and inorganic compounds including liquid crystals, carboranes, proteins, peptides, oligonucleotides using both positive and negative ionization modes.