Postdoc Scientist-Pharmaceutical Develoment (Small Molecule) @ Wolfe Laboratories

JOB SUMMARY: We require an experienced physical organic chemist with broad knowledge of and significant hands on experience with small molecule analytical technology including chromatographic and physical characterization methods. This individual will plan and execute experiments in physicochemical analysis and structural characterization.

 

DUTIES AND RESPONSIBILITIES:

 

  • Evaluate physicochemical properties of small molecules relevant to drug development and subsequently communicate the interpretation and implication of results to clients.
  • Develop analytical methods and characterize product variants
  • Execute and oversee specialized analytical testing and generation of technical documents
  • Maintain a strong awareness of current scientific literature, particularly in the area of drug substance characterization, and actively apply new concepts as appropriate.
  • Design experiments to develop pre-clinical and clinical formulations of drug candidates to support drug discovery and development.
  • Design experiments to determine the stability in prototype clinical formulations, to detect and identify the decomposition products, and to achieve formulations with acceptable shelf-life.
  • Perform laboratory experiments related to the above.
  • Create presentations for outside scientific meetings and conferences to showcase Wolfe Laboratories’ scientific leadership in the field of small molecule analysis and characterization.
  • Interface with clients to develop an in-depth understanding of client objectives and define solutions to meet their program requirements
  • Develop compelling approaches and solutions to address client needs
  • Write persuasive proposals for the projects
  • Regularly interact with clients to keep them abreast of project progress
  • Write and review interim and final reports.
  • Ph.D. in Physical Organic Chemistry, Pharmaceutical Chemistry, Medicinal Chemistry, Process Chemistry, Chemical Engineering, or closely related discipline
  • In depth expertise in physical organic chemistry and the structural characterization of small molecules as they relate to the pre-formulation and formulation development of new drugs
  • Expertise in the field of physicochemical analysis and structural characterization
  • Hands-on experience with method development as well as analytical methods used for physicochemical characterization of pharmaceutical products such as spectroscopy and HPLC analysis.
  • A demonstrated drive to apply technical knowledge to developing drug formulations
  • Established track record of significant contributions as an individual technical expert as well as a leader of small teams
  • Outstanding written and oral communication skills as well as polished and persuasive client presentation skills
  • Capability with DSC, TGA, and/or lyophilization
  • Experience in creating and delivering trainings

 

WHERE THIS JOB COULE LEAD:

At Wolfe Laboratories Inc., we pride ourselves on retaining and growing our team members, and ensuring they are developing to their full potential. This position can provide many different avenues for advancement, including:

  • Training      towards becoming a Project Manager
  • Leader      of an innovative business line
  • Become      a Lead Technical Researcher
  • Managing      a team of Postdoctoral employees

Interested candidates are requested to email a copy of their resume with a cover letter and unofficial transcripts to: This email address is being protected from spambots. You need JavaScript enabled to view it. .

Wolfe Laboratories, Inc. (WLI), founded in 1999, and located in Watertown, MA, is a premier contract research organization that provides integrated early drug development solutions to the biopharmaceutical industry. Wolfe Laboratories is an essential element of the drug development ecosystem, recognized by global and virtual biopharmaceutical companies as a science-driven organization whose mission is to provide outstanding discovery and development services tailored to its clients’ needs for rational formulation development. Wolfe Laboratories integrates the critical path components of early development to ensure that programs advance while meeting rigorous scientific demands with flexibility to address dynamic challenges and aggressive timelines. Wolfe Laboratories’ vision is to improve human health, and we continue to strive towards that goal by embracing our core values of integrity, excellence and teamwork. The company has a high percentage of repeat clients, which is a testament to its long-term commitment of continual investment in its capabilities to meet biopharma’s growing demand for high quality, integrated early development services.

For more information visit us at: www.wolfelabs.com.

Wolfe Laboratories, Inc is an Equal Employment Opportunity employer.

Postdoc Scientist-Pharmaceutical Development @ Wolfe Laboratories

JOB SUMMARY: We require a highly motivated Postdoctoral Scientist to work on protein stability & aggregation as it relates to therapeutic protein development. The current postdoctoral project is designed to understand the fundamental mechanism/s of protein instability, sub-visible particulate formation and aggregation using variety of chromatographic, biophysical and biochemical tools.

 

DUTIES AND RESPONSIBILITIES:

  • Evaluate physical and biophysical properties of peptides, proteins, and bioconjugates relevant to drug development and subsequently communicate the interpretation and implication of results to clients.
  • Develop analytical and high throughput biophysical methods to characterize product variants
  • Execute and oversee specialized analytical testing and generation of technical documents
  • Maintain a strong awareness of current scientific literature, particularly in the area of protein characterization, and actively apply new concepts as appropriate.
  • Design experiments to develop pre-clinical and clinical formulations of drug candidates to support drug discovery and development.
  • Design experiments to determine the stability in prototype clinical formulations, to detect and identify the decomposition products, and to achieve formulations with acceptable shelf-life.
  • Perform laboratory experiments related to the above.
  • Create presentations for outside scientific meetings and conferences to showcase Wolfe Laboratories’ scientific leadership in the field of protein analysis and characterization.
  • Interface with clients to develop an in-depth understanding of client objectives and define solutions to meet their program requirements
  • Develop compelling approaches and solutions to address client needs
  • Write persuasive proposals for the projects
  • Regularly interact with clients to keep them abreast of project progress
  • Write and review interim and final reports.
  • Ph.D. in Biochemistry, Biophysics, Chemistry, Biomolecular engineering, Organic Chemistry, Chemical engineering or closely related disciplines
  • In depth experience in the area of protein biophysics involving structure-folding-stability relationships. This includes purification, stability, kinetics and thermodynamics of folding of monomeric proteins, particularly as they relate to the pre-formulation and formulation development of new drugs
  • Hands-on experience with chromatographic method development as well as techniques used for biophysical characterization of biopharmaceutical products such as calorimetry, spectroscopy, higher order structure analysis, protein mass spectroscopy, CE, HPLC, ELISA, and carbohydrate analysis.
  • Strong knowledge of Organic Chemistry principles
  • A demonstrated drive to apply technical knowledge to developing drug formulations
  • Established track record of significant contributions as an individual technical expert

 

WHERE THIS JOB COULD LEAD:

At Wolfe Laboratories Inc., we pride ourselves on retaining and growing our team members, and ensuring they are developing to their full potential. This position can provide many different avenues for advancement, including:

  • Training      towards becoming a Project Manager
  • Leader      of an innovative business line
  • Become      a Lead Technical Researcher
  • Managing      a team of Postdoctoral employees

Interested candidates are requested to email a copy of their resume with a cover letter and unofficial transcripts to: This email address is being protected from spambots. You need JavaScript enabled to view it.

Wolfe Laboratories, Inc. (WLI), located in Watertown, MA, is a premier contract research organization that provides integrated early drug development solutions to the biopharmaceutical industry. Wolfe Laboratories is an essential element of the drug development ecosystem, recognized by global and virtual biopharmaceutical companies as a science-driven organization whose mission is to provide outstanding discovery and development services tailored to its clients’ needs for rational formulation development. Wolfe Laboratories integrates the critical path components of early development to ensure that programs advance while meeting rigorous scientific demands with flexibility to address dynamic challenges and aggressive timelines. Wolfe Laboratories’ vision is to improve human health, and we continue to strive towards that goal by embracing our core values of integrity, excellence and teamwork. The company has a high percentage of repeat clients, which is a testament to its long-term commitment of continual investment in its capabilities to meet biopharma’s growing demand for high quality, integrated early development services.

For more information visit us at: www.wolfelabs.com.

Wolfe Laboratories, Inc is an Equal Employment Opportunity Employer.

Tenure-Track Assistant Professor

The Department of Chemistry at the University of Missouri-Kansas City invites applications for a tenure-track Assitant Professor in the area of synthetic organic, inorganic, or materials chemistry to start August 2015. A Ph.D. in chemistry or an allied discipline is required, and postdoctoral or comparable research experience is preferred.  The successful candidate is expected to establish a vigorous, externally funded research program and to provide effective teaching at the undergraduate and graduate levels.

Review of applications begins upon receipt and continues until the position is filled.  Applications are only accepted online at www.umkc.edu/hr/jobsearch.  Please combine all applicatin materials (cover letter, full cirriculum vitae, research plans and a statement of teaching philosopy) into one PDF or Microsoft Word document and upload as your resume attachment.  Limit document name to 50 characters.  Maximum size limit is 11MB.  Do not include special characters (e.g.,/,&,%, etc.).  Arrange for three official letters of reference to be sent to: Chair, Search Committee via e-mail to This email address is being protected from spambots. You need JavaScript enabled to view it.

UMKC is an Equal Opportunity/Access/Affirmative Action/Pro Disabled & Veteran Employer

2015 Fall BME Faculty Position Opening (NTHU Taiwan)

Faculty Position Opening

Assistant/Associate/Full Professor Institute of Biomedical Engineering, NTHU

The Institute of Biomedical Engineering, National Tsing Hua University, seeks highly qualified individuals for 2 positions in the assistant, associate or full professorship levels. The candidate must have a Ph.D. degree in engineering or science, an outstanding record of accomplishments in research (cellular mechanics, bioMEMS, or biomaterials) and enthusiasm in teaching. Application portfolio including curriculum vitae, copies of diplomas, copies of undergraduate and graduate transcripts, full publication list, teaching and research plans, contact information (names, mailing addresses, emails, phone numbers) of three referees (only a list is needed upon submission) and the CV at-a-glance (as attached or available on http://my.nthu.edu.tw/~bme/index.html) should be sent to Ms. Peggy Sung at This email address is being protected from spambots. You need JavaScript enabled to view it. by Jan. 30, 2015.

Chia-hsing (Peggy) Sung

Secretary

Institute of Biomedical Engineering

National Tsing Hua University

Taiwan

Tel: +866-3-571-5131 ext. 35500

Website: http://my.nthu.edu.tw/~bme/index.html

 

 

 

Two Visiting Positions at The College of Wooster

Two Visiting Assistant Professors of Chemistry

The Department of Chemistry at the College of Wooster invites applications of two full-time one year visting Assistant Professors of Chemistry to begin August 2015.  One position focused in organic chemistry and the second in inorganic chemistry.  Primary teaching in the area of expertise (organic chemistry or inorganic chemistry) and as well as courses for first year students. Ph.D. by the time of appointment required.

Application materials should be submitted to This email address is being protected from spambots. You need JavaScript enabled to view it. .  Please prepare a single PDF containing cover letter, cirriculum vitae, undergraduate and graduate transcripts, and a one-page statment descring interest in teaching in teh undergraduate liberal arts setting. 

Three letters of recommendation should also be provided under separate cover.

Questions about teh position may be directed to Dr. Mark Snider (This email address is being protected from spambots. You need JavaScript enabled to view it. )

Review of applications begins January 12, 2015 and will continue until appointments are made.

The College of Wooster is an independent college of the liberal arts and sciences with a commitment to excellence in undergradute education.  The College values diversity, strives to attract qualified women and minority candidates, and encourages individuals belonging to these groups to apply.  Wooster seeks to ensure diversity by its policy of making appointments without regard to age, sex, color, race, creed, religion, national origin, disability, sexual orientation, gender identity and expression, or political affiliation.  The College of Wooster is an Equal Opprotunity/Affirmative Action Employer.  Employment is subject to federal laws requiring verification of identity and legal right to work in the United States as required by the Immigration Reform and Control Act.  The College of Wooster is a drug-free workplace.

http://www.wooster.edu

MCAT Instructor

Princeton Review-Colorado is currently recruiting MCAT Instructors to teach Biology, Physics, General Chemistry, and Organic Chemistry. The job opportunity is posted on CU's Job Board. More information is available on our national website http://www.princetonreview.com/teach-for-the-princeton-review.aspx and on the CU Job Board http://studentjobs.colorado.edu

Thanks,

Robin Packer